骊城公安局最年轻的法医齐思哲（罗云熙饰），因一场车祸失去了女友俞菲，但他发觉意外的背后似乎隐藏着神秘的幕后推手。为了调查真相，齐思哲入职成为河城市公安局的刑侦法医，却被迫卷入一桩桩令人细思极恐的奇诡悬案之中，身亡许久的被害者被重重蛛丝包裹，失踪的尸体出现在标本室的福尔马林中……在侦破过程中，他与祝青越（刘雅瑟饰），韩烽（江奇霖饰）强强联合，抽丝剥茧屡破奇案，而牵涉当年俞菲之死的“原钻”毒品案，也逐渐展露冰山一角……
Season 5 finds Murder, She Wrote's intrepid Jessica Fletcher in fine sleuthing form, and venturing farther afield from Cabot Cove--a good thing, since at the rate the murders have been happening, that town would be nearly cleaned out. Some of the best episodes take place in more exotic locales like New York (dead man on the street, wearing just one shoe), Montana (a publishing convention gone horribly wrong) and West Virginia (two whistle-blowers at a coal company found gruesomely murdered). Angela Lansbury sparkles with determination and bonhomie, hitting her stride and then some. Jessica's own life backstory is even filled out tantalizingly, especially in the episode "The Last Flight of the Dixie Damsel," in which an investigation is launched into a mysterious cargo plane that is linked, she learns to her horror, to her late husband. The series' other delight is watching for cameos by stars of a certain age, and this season doesn't disappoint, with appearances by Roddy McDowall, Shelley Fabares, and Dinah Shore--but also some up-and-comers like Megan Mullally (proof positive that the Will & Grace whine was a put-on) and future satirist Bill Maher.
半年间，SNK剧变，总监余英飞离职、门外汉古肇华空降。张家妍虽掌权却难服众。刘艳的公开平台崛起，动摇传统媒体地位，连已入官场的许诗晴亦被卷入新旧媒体的角力。文慧心于此时复出，昭告世人：新闻女王的地位永远不可撼动！
