该剧改编自步月浅妆的小说《权宠之仵作医妃》,讲述大理寺卿沈毅因卷入晋王案,全家惨遭灭门,其女沈莞借用秦府九娘子秦莞的身份逃到荆州。原本柔弱可欺的秦莞“性情大变”,不仅会治病救人,还能剖尸探案,顺带将秦府的伯母庶妹姨娘刁奴治得服服帖帖。探案期间秦结识了睿王世子燕迟,燕迟一心为晋王翻案,与秦莞为父昭雪的目标不谋而合,二人一起回京,途中联手破获了各式诡谲大案。回京后,一具意外发现的骸骨让晋王案得以重提,燕迟和秦莞一起慢慢接近了案件的真相,发现了皇宫里深藏的惊天秘密。
The story of a young group of siblings pretty much abandoned by their parents, surviving by their wits - and humor - on a rough Manchester council estate. Whilst they won't admit it, they need help and find it in Steve, a young middle class lad who falls for Fiona, the oldest sibling, and increasingly finds himself drawn to this unconventional and unique family. Anarchic family life seen through the eyes of an exceptionally bright fifteen year old, who struggles to come of age in the context of his belligerent father, closeted brother, psychotic sister and internet porn star neighbors.
该剧根据Beth Macy撰写的同名畅销书改编,迈克尔·基顿扮演老派医生塞缪尔·芬尼克斯,他以仁慈和同情心对待自己的工作,但他发现自己陷入了大制药公司致命的秘密之中。