为了让罹患血癌的凯特(苏菲亚·威希涅瓦 Sofia Vassilieva 饰)能够活下去,父母通过基因技术“制造”了与凯特的基因完美配型的小女儿——安娜(阿比吉尔·布莱斯林 Abigail Breslin 饰)。安娜感觉自己只是姐姐凯特的“药罐子”,11年来,凡是在凯特有需要的时候,无论是脐带血还是白血球、肝细胞、骨髓,她都得源源不断的向凯特提供。然而,即使有孤注一掷的妈妈(卡梅隆·迪亚茨 Cameron Diaz 饰)、无可奈何的爸爸,以及身边所有人的爱,凯特的情况还是越来越糟,肾功能的衰竭必须要年仅11岁的安娜捐献出自己的一个肾。这一次,安娜选择了拒绝,并且寻找到律师坎贝尔把母亲告上法庭,她要捍卫自己的身体。然而,法庭上哥哥杰西却吐露了另一番真相…… 本片根据美国当代畅销书女王朱迪·皮考特(Jodi Picoult)的同名小说改编。
After seventeen years in prison, the former respected Parisian banker Paul Lavond flees with his friend, the lunatic scientist Marcel that is researching with his wife Malita the miniaturization of animals and human beings to improve the resources of mankind. Paul Lavond was framed for robbery by his scoundrel associates Emil Coulvet, Charles Matin and Victor Radin that had stolen his business while his family was doomed to shame, poverty and tragedy. When Marcel reduces the retarded servant Lachna, he learns that the woman is motionless and only responds to the control of his brain and has a heart attack. After the death of Marcel, Paul Lavond sees the chance to use the miniaturization process as instrument of vengeance and he travels to Paris with the insane Malita disguised of Madame Mandilip, a nice old lady and owner of a dolls store. Paul Lavond, using the identity of Madame Mandilip, befriends his resented and estranged daughter Lorraine Lavond and plots a scheme to revenge and vindicate his family name.